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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 4677063 B1

PDFFull Text
Date of Patent:
Jun. 30, 1987

Filed:

Jul. 30, 1985

Human tumor necrosis factor

Applicant:
Inventors:

David F Mark, Danville, CA (US);

Alice M Wang, Walnut Creek, CA (US);

Martha B Ladner, Richmond, CA (US);

Abla A Creasey, Piedmont, CA (US);

Leo S Lin, Fremont, CA (US);

Janelle Van Arsdell, Richmond, CA (US);

Assignee:

Cetus Corporation, Emeryville, CA (US);

Attorneys:

Halluin; Albert P.

Murashige; Kate H.

Primary Examiner:

Thomas G Wiseman

Assistant Examiner:

Robin Teskin

Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ; A61K / ;
U.S. Cl.
CPC ...
435 68 ; 4351723 ; 435253 ; 435317 ; 514-8 ; 514 12 ; 530350 ; 530351 ; 530395 ; 530808 ; 424 85 ; 424 88 ; 536 27 ;
Abstract

Human tumor necrosis factor (TNF) has been prepared using recombinant methods. A human promyelocytic leukemia cell line has been induced using an improved induction procedure, and the TNF purified to homogeneity. Methods, vectors, and cells useful in obtaining human TNF in practical amounts are disclosed. Muteins having N-terminal deletions, which muteins have superior biological activity, are also disclosed.

Find Patent Forward Citations

Mark, David. (1987). Human tumor necrosis factor (U.S. Patent No. 4677063). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4677063

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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