The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 1986
Filed:
Mar. 24, 1983
Applicant:
Inventors:
Andrew S Janoff, Lawrenceville, NJ (US);
Marc J Ostro, North Brunswick, NJ (US);
Alan L Weiner, Plainsboro, NJ (US);
Gerald Weissmann, New York, NY (US);
James R Seibold, Piscataway, NJ (US);
Assignee:
The Liposome Company, Inc., Princeton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; B32B / ; B32B / ; B32B / ; A01N / ; A61K / ;
U.S. Cl.
CPC ...
436507 ; 436506 ; 436829 ; 4284022 ; 424-71 ; 424 38 ;
Abstract
An assay for detecting SLE antibodies utilizing a novel liposome composition in which there is entrapped a divalent cation responsive indicator. The presence of such antibodies is detected by their stabilization of the supermolecular structure of the liposomes. Such stabilization can be detected, and in certain cases, caused by, the addition of magnesium or calcium ions.