The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 1982
Filed:
Jul. 21, 1980
Applicant:
Inventor:
Kenneth P Shephard, Portage, MI (US);
Assignee:
The Upjohn Company, Kalamazoo, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J / ;
U.S. Cl.
CPC ...
2602 / ; 26039745 ; 2603973 ; 2602 / ;
Abstract
Two processes are disclosed (one-pot and two-pot) for the transformation of a 6.beta.-fluoro-.DELTA..sup.1,4 -3-keto steroid (IV) to a 6.alpha.-fluoro-.DELTA..sup.1,4 -3-keto steroid (VI). These processes permit the introduction of a fluorine atom at the 6.alpha. position of a .DELTA..sup.1,4 -3-keto steroid where previously the .DELTA..sup.1 double bond could not be introduced until after the 6.alpha.-fluorine atom was present. The 6.alpha.-fluoro-.DELTA..sup.1,4 -3-keto steroids (VI) are intermediates useful in the production of pharmacologically active steroids.