The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 18, 1982

Filed:

Feb. 28, 1980
Applicant:
Inventors:

Wolfgang Gruber, Tutzing, DE;

Helmut Lenz, Tutzing, DE;

Siegfried Looser, Weilheim, DE;

Hans-Ralf Linke, Raisting, DE;

Assignee:

Boehringer Mannheim GmbH, Mannheim-Waldhof, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; C12Q / ; C12N / ;
U.S. Cl.
CPC ...
435-7 ; 435-8 ; 435 17 ; 435184 ;
Abstract

A method for the determination of creatine kinase-MB in serum by immunological exclusion of sub-unit M and measurement of the sub-unit B for the determination of creatine kinase, the improvement comprising, for the purpose of excluding the sub-unit M, adding to the reaction mixture comprising determination reagents and the creatine kinase-containing sample, monovalent fragments obtained from antibodies against the sub-unit M by proteolytic cleavage under reducing conditions.


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