The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 1981
Filed:
Oct. 17, 1977
Applicant:
Inventors:
William G Thilly, Cambridge, MA (US);
Thomas R Skopek, Stafford Springs, CT (US);
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ;
U.S. Cl.
CPC ...
435-6 ; 435 34 ; 435172 ;
Abstract
An assay is disclosed for determining mutagenic damage caused by the administration of a known or suspected mutagen to bacterial cells such as Salmonella typhimurium. After administration of or exposure to a mutagenic agent, the bacterial cells are plated in the presence of a purine analog and resistance to purine analogs is used as the genetic marker. This bioassay system can be used by genetic toxicologists to determine the potential genetic hazards from the use of a variety of suspected or known mutagens, including newly-developed chemicals.