The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 1979
Filed:
Dec. 02, 1977
Applicant:
Inventors:
Hugh L Dryden, Jr, Deerfield, IL (US);
Gayle M Webber, Wilmette, IL (US);
Assignee:
G. D. Searle & Co., Skokie, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J / ;
U.S. Cl.
CPC ...
26023957 ;
Abstract
A process for preparing 17-hydroxy-3-oxo-17.alpha.-pregna-4,6-diene-21-carboxylic acid .gamma.-lactone by contacting 17-hydroxy-3-oxy-17.alpha.-pregna-3,5-diene-21-carboxylic acid .gamma.-lactone with an appropriate halogenating agent in the presence of an amine base, the corresponding hydrohalide salt thereof, and approximately 1-2 molar equivalents (relative to the lactonic starting material) of water, using a cold solvent as the contact medium, and heating the resultant mixture with a dehydrohalogenating agent, is disclosed.