The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 29, 1977

Filed:

Jan. 08, 1976
Applicant:
Inventors:

Murray Garber, Trenton, NJ (US);

Lawrence James Ross, Martinsville, NJ (US);

Walter Joseph Stepek, Trenton, NJ (US);

Assignee:

American Cyanamid Company, Stamford, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ;
U.S. Cl.
CPC ...
2603 / ; 2603 / ;
Abstract

There is provided a process for the preparation of 3,5-disubstituted pyrazoles which involves: A. the reaction of a methyl ketone, such as acetophenone or an appropriate derivative thereof, with an appropriate aldehyde, such as benzaldehyde in the presence of base to form a 1,3-disubstituted .alpha.,.beta.-unsaturated ketone, such as chalcone or a substituted chalcone, B. the acidification of said .alpha.,.beta.-unsaturated ketone, followed by treatment of the acidified reaction mixture with hydrazine to form a disubstituted pyrazoline, and C. the catalytic dehydrogenation of said pyrazoline to yield the desired 3,5-disubstituted pyrazole.


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