The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 25, 1977

Filed:

Jan. 15, 1975
Applicant:
Inventors:

Stratis Avrameas, La Celle Saint Cloud, FR;

Georges Broun, Rouen, FR;

Eric Selegny, Rouen, FR;

Daniel Thomas, Rouen, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07G / ; C07G / ;
U.S. Cl.
CPC ...
195 68 ; 195 59 ; 195 63 ; 195D / ; 2601 / ; 424 94 ;
Abstract

Articles containing active proteins, such as enzymes, crosslinked to an inactive protein are prepared by dispersing and reacting in a solvent an active protein and an inactive protein simultaneously with a crosslinking agent to crosslink the active and inactive proteins together. The degree of crosslinking can be controlled by introducing tris (hydroxymethyl) aminomethane in an amount sufficient to stop chain growth. Optionally, an inert carrier may be present during crosslinking. The resultant crosslinked active and inactive proteins can be in various forms such as solutions, suspensions, gels, films, membranes, granules, pills or tablets.


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