The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 08, 1976
Filed:
Apr. 10, 1974
Koji Kawashima, Chofu, JA;
Keiji Umeda, Tokyo, JA;
Abstract
Water-insoluble enzymes are prepared by mixing an enzyme with at least one water soluble monomer selected from the group consisting of acrylamide, bisacrylamide, acrylic acid, sodium acrylate, potassium acrylate and calcium acrylate, freezing the resulting mixture at a temperature below about -5.degree.C and irradiating the frozen mixture with gamma rays or x-rays under aerobic conditions to polymerize said monomer and entrap the enzyme in the resulting polymer material. The frozen irradiated polymer material can be thawed at room temperature or can be lyophilized to produce a spongelike, membrane form that maintains its structure when immersed in water. Before freezing the enzyme and monomer mixture, an organic substance can be incorporated which promotes polymerization yield and protects the enzyme from radiation inactivation.