The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2026
Filed:
Mar. 01, 2023
Masayuki Yumoto, Kanagawa, JP;
Yudai Kawashima, Kanagawa, JP;
Hikaru Watanabe, Kanagawa, JP;
Toshihiko Hosoya, Tokyo, JP;
Minoru Ko, Tokyo, JP;
Masayuki Yumoto, Kanagawa, JP;
Yudai Kawashima, Kanagawa, JP;
Hikaru Watanabe, Kanagawa, JP;
Toshihiko Hosoya, Tokyo, JP;
Minoru Ko, Tokyo, JP;
Ricoh Company, Ltd., Tokyo, JP;
Elixirgen Scientific, Inc., Baltimore, MD (US);
Abstract
There is provided a production method for microglia, including a step of introducing, into pluripotent stem cells, a nucleic acid including an open reading frame of a transcription factor that increases expression of a Complement C3 (C3) gene. In the production method, the transcription factor is selected from the group consisting of SPI1, CEBPA, PTAFR, FLI1, MEF2C, EGR2, RUNX1, TNF, CEBPB, IKZF1, KLF6, NFIC, ELF4, PAX8, PRDM1, MEF2A, and NR4A3.