The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2026
Filed:
Mar. 02, 2023
Applicants:
Jsr Corporation, Tokyo, JP;
Keio University, Tokyo, JP;
Inventors:
Mitsuru Ishikawa, Tokyo, JP;
Hideyuki Okano, Tokyo, JP;
Assignees:
JSR CORPORATION, Tokyo, JP;
KEIO UNIVERSITY, Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/079 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0622 (2013.01); C12N 2501/10 (2013.01); C12N 2501/60 (2013.01); C12N 2506/45 (2013.01);
Abstract
A method is provided for producing astrocyte-like cells, including (A) upregulating transcription factors including SRY-box transcription factor 9 (SOX9), nuclear factor IA (NFIA), and nuclear factor IB (NFIB) in human pluripotent stein cells and (B) culturing the human pluripotent stem cells, in which the transcription factors are upregulated, and consequently differentiating the human pluripotent stem cells into astrocyte-like cells.