The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2026

Filed:

Jun. 16, 2022
Applicant:

Technion Research & Development Foundation Limited, Haifa, IL;

Inventors:

Yoav D. Livney, Haifa, IL;

Yechezkel Kashi, Haifa, IL;

Stav Peled, Haifa, IL;

Shay Freilich, Haifa, IL;

Adi Seifert, Haifa, IL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A23L 33/21 (2016.01); A61K 38/40 (2006.01); A61K 47/61 (2017.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
A61K 47/6921 (2017.08); A23L 33/21 (2016.08); A61K 38/40 (2013.01); A61K 47/61 (2017.08); A61K 47/64 (2017.08);
Abstract

Provided herein is a particle made of a protein or a peptide covalently bound to a prebiotic carbohydrate, thereby forming a conjugate. The particle may be used for selectively promoting probiotic bacteria growth in the intestine, particularly the colon and may be used to selectively deliver additional probiotic growth factors, or other bioactives and drugs to probiotic bacteria in the intestine, particularly to the colon. Furthermore, provided herein are methods for preparing the particle, and for delivering a substance bound to, or entrapped within the particle, into the gastrointestinal tract of a subject in need thereof.


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