The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 25, 2026
Filed:
Dec. 09, 2022
Pendar Technologies, Inc., Cambridge, MA (US);
John P. Romfh, Palo Alto, CA (US);
Daryoosh Vakhshoori, Cambridge, MA (US);
Peili Chen, Andover, MA (US);
Shannon Tessier, Ashland, MA (US);
Reinier De Vries, Utrecht, NL;
Stephanie Cronin, Boston, MA (US);
Pendar Technologies, Inc., Cambridge, MA (US);
The General Hospital Corporation, Boston, MA (US);
Abstract
The present technology includes a system and method for monitoring a donor organ tissue using Raman spectroscopy. The technology enables real-time quantification of the mitochondrial redox state in the tissue sample taken from an organ intended for transplant using a compact device. The system is based on resonance Raman spectroscopy which can quantify a mitochondrial redox state in tissues using a Resonance Raman Reduced Mitochondrial Ratio. The mitochondrial redox state of the tissue sample acts as a marker of tissue function and may distinguish healthy versus damaged tissue. Moreover, these measures may correlate with transplantation outcomes.