The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 25, 2026

Filed:

Feb. 16, 2022
Applicant:

The John Hopkins University, Baltimore, MD (US);

Inventors:

Hai-Quan Mao, Baltimore, MD (US);

Yining Zhu, Baltimore, MD (US);

Yizong Hu, Baltimore, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12N 5/071 (2010.01); C12N 7/00 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); C12N 5/0686 (2013.01); C12N 7/00 (2013.01); B82Y 5/00 (2013.01); C12N 2740/15051 (2013.01);
Abstract

A scalable method for producing DNA/polycation particles having an optimal, defined particle size with multiple virus assembly plasmids for efficient transfection of viral production cells in suspension cultures. The presently disclosed DNA/polycation particles yield superior and reproducible transfection activity and shelf stability in the suspension form and can be used as an off-the-shelf product. The presently disclosed DNA/polycation particle formulation can potentially simplify and streamline the viral manufacturing process and improve production quality and consistency.


Find Patent Forward Citations

Mao, Hai-Quan. (2026). Composition of shelf-stable plasmid dna/polyethyleneimine (pei) particles with defined sizes for viral vector production and method for preparation of the same (U.S. Patent No. 12716073). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12716073

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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