High-throughput high-pressure small-angle neutron scattering sample cells and environments

Abstract

High-throughput high-pressure (HT HP) sample cells and sampling environments are disclosed herein. The HT HP sample cells include a top cell member and a bottom cell member that can be sealed together enclosing a sample in a pressure transmitter chamber. Further, the HT HP sample cells include a compressible, circular internal separator for compressing a sub-mL soft matter liquid sample. Further, the radiation beam windows of the HT HP sample cells are integral to the HT HP sample cell members. The novel and innovative HT HP sample cell design enables SANS measurements of the soft matter liquid sample when exposed to extreme temperatures and pressures without exhibiting leakage or cross-contamination of the soft matter liquid sample with the pressurizing fluid. Methods for using the HT HP sample cells in a pressurizing system for SANS analysis are also disclosed.