The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2026

Filed:

Jan. 27, 2022
Applicants:

Lanzhou Chemspec Technology Co., Ltd, Lanzhou, CN;

Shanghai Chemspec Corporation, Shanghai, CN;

Inventors:

Li He, Shanghai, CN;

Xiaoliang Li, Shanghai, CN;

Zhenli Liu, Shanghai, CN;

Zhong Tian, Shanghai, CN;

Hanqing Duan, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/61 (2006.01); B01J 31/02 (2006.01); C07D 271/10 (2006.01);
U.S. Cl.
CPC ...
C07D 213/61 (2013.01); B01J 31/0247 (2013.01); B01J 31/0274 (2013.01); C07D 271/10 (2013.01); B01J 2231/005 (2013.01); B01J 2531/002 (2013.01);
Abstract

A first aspect of the present invention provides a method for the preparation of 2-chloro-5-chloromethylpyridine, comprising: performing a cyclization reaction on 4,5-dichloro-4-methoxypentanenitrile in presence of a silicon compound and an acylamide compound to obtain 2-chloro-5-chloromethylpyridine. Another aspect of the present invention provides a method for preparation of 2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole, comprising: performing a cyclization reaction on 1-(chloroacetyl)-2-(trifluoroacetyl)hydrazine in a presence of a silicon compound and an acylamide compound to obtain 2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole. The silicon compound or/and acylamide compound provided by the present invention serve as cyclization reagents and have high efficiency.


Find Patent Forward Citations

He, Li. (2026). Use of silicon compounds in cyclization reactions (U.S. Patent No. 12686662). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12686662

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