Natural efficient self-assembled photothermal antibacterial nanoparticle, preparation method therefor and use thereof

Abstract

A preparation process of the natural efficient self-assembled photothermal antibacterial nanoparticle is provided that includes mixing a solution of berberine in methanol and a solution of rhein of methanol to obtain a mixed solution, and then mixing the mixed solution with water and performing self-assembly reaction to obtain a self-assembled nanoparticle solution; and mixing the self-assembled nanoparticle solution with a solution of chromium chloride in methanol, and performing coordination reaction to obtain the natural efficient self-assembled photothermal antibacterial nanoparticle. The natural efficient self-assembled photothermal antibacterial nanoparticle prepared by the present invention can quickly raise the temperature under irradiation of near-infrared long-wave light, thus playing a role in instantaneous broad-spectrum sterilization. Because the berberine and the rhein have antibacterial effects, the prepared nanoparticle has a double synergistic sterilization effect under the irradiation of near-infrared long-wave light.