The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2026

Filed:

May. 09, 2019
Applicants:

Roche Molecular Systems, Inc., Pleasanton, CA (US);

Sandstone Diagnostics, Inc., Pleasanton, CA (US);

Inventors:

Jon Epperson, Pleasanton, CA (US);

Laura Fredriksen, Pleasanton, CA (US);

Kyungjin Hong, Pleasanton, CA (US);

Jenq-Thun Li, Pleasanton, CA (US);

Bhairavi Rajiv Parikh, Pleasanton, CA (US);

Ulrich Schaff, Pleasanton, CA (US);

Assignees:

Roche Molecular Systems, Inc., Pleasanton, CA (US);

Sandstone Diagnostics, Inc., Pleasanton, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12Q 1/06 (2006.01); C12Q 1/18 (2006.01); G01N 1/30 (2006.01); G01N 15/06 (2024.01); G01N 33/487 (2006.01); G01N 15/01 (2024.01); G01N 15/075 (2024.01);
U.S. Cl.
CPC ...
C12Q 1/06 (2013.01); B01L 3/502761 (2013.01); C12Q 1/18 (2013.01); G01N 1/30 (2013.01); G01N 15/06 (2013.01); G01N 33/487 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0809 (2013.01); B01L 2300/0861 (2013.01); G01N 2001/302 (2013.01); G01N 15/01 (2024.01); G01N 15/075 (2024.01);
Abstract

A cartridge for determining a concentration of target cells within a sample includes a separation portion and a detection portion. The separation portion includes a first and second surface defining a separation chamber. The separation portion can contain a density medium having a density greater than a density of a first portion of the sample and less than a density of a second portion of the sample (that includes the target cells). The separation chamber can be fluidically coupled to an inlet reservoir such that the sample can pass from the inlet reservoir to the separation chamber during rotation. The detection portion includes a detection surface that forms a boundary of a detection chamber. The detection surface is nonparallel to the first surface such that the target cells impinge on the detection surface when passing into the detection chamber. The detection surface is configured to capture the target cells.


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