The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 23, 2026

Filed:

Feb. 07, 2019
Applicant:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Inventors:

James Eberwine, Philadelphia, PA (US);

Jai-Yoon Sul, Cherry Hill, NJ (US);

Paulo Arratia, Philadelphia, PA (US);

David Gagnon, Washington, DC (US);

Ram Gona, Philadelphia, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12M 1/32 (2006.01); C12M 3/06 (2006.01);
U.S. Cl.
CPC ...
B01L 3/50273 (2013.01); C12M 23/12 (2013.01); C12M 23/16 (2013.01); C12M 23/22 (2013.01); C12M 25/14 (2013.01); B01L 2200/0684 (2013.01); B01L 2300/0877 (2013.01); B01L 2400/0487 (2013.01);
Abstract

The present invention provides microfluidic devices capable of generating a flow of fluids within a chamber. The flow of fluids mix within the chamber to form a gradient of concentrations. The chamber is capable of accepting a cell culture and is accessible to retrieve the cell culture. The microfluidic devices are compatible with standard laboratory microscopes for optical analyses of the chamber.


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