The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 16, 2026

Filed:

Apr. 06, 2016
Applicant:

University of Maryland, Baltimore, Baltimore, MD (US);

Inventors:

Stefanie N Vogel, Columbia, MD (US);

Alexander Mackerell, Jr., Baltimore, MD (US);

Assignee:

University of Maryland, Baltimore, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/196 (2006.01); A61K 31/11 (2006.01); A61K 31/136 (2006.01); A61K 31/18 (2006.01); A61K 31/381 (2006.01); A61K 31/437 (2006.01); A61K 31/4406 (2006.01); A61K 31/4439 (2006.01); A61K 31/513 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01); A61K 31/5355 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/196 (2013.01); A61K 31/11 (2013.01); A61K 31/136 (2013.01); A61K 31/18 (2013.01); A61K 31/381 (2013.01); A61K 31/437 (2013.01); A61K 31/4406 (2013.01); A61K 31/4439 (2013.01); A61K 31/513 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/5355 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61P 29/00 (2018.01);
Abstract

The present invention is drawn to therapeutics and methods of inhibiting signaling by TLR2. The invention provides a method of treating an inflammatory disease or condition in a subject comprising administering to the subject a therapeutically effective amount of a compound of the invention or salt, solvate, hydrate, prodrug, metabolite, or combination thereof.


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