The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2026

Filed:

Jun. 18, 2021
Applicants:

Shanghai Synergy Pharmaceutical Sciences Co., Ltd., Shanghai, CN;

Zhejiang Huahai Pharmaceutical Co., Ltd., Zhejiang, CN;

Inventors:

Xin Xu, Shanghai, CN;

Jia Chen, Shanghai, CN;

Guan Wang, Shanghai, CN;

Linli Zhang, Shanghai, CN;

Qingyun Jiang, Shanghai, CN;

Chenghao XI, Shanghai, CN;

Kang Sun, Shanghai, CN;

Xiaojuan Zhang, Shanghai, CN;

Chunqiao Chen, Shanghai, CN;

Shuai Li, Shanghai, CN;

Qiang Li, Shanghai, CN;

Liangze Xia, Shanghai, CN;

Ying Wang, Shanghai, CN;

Xiaoer Xia, Shanghai, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); A61P 11/00 (2006.01); A61P 19/02 (2006.01); A61P 35/00 (2006.01); A61P 37/06 (2006.01); C07D 241/36 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 11/00 (2018.01); A61P 19/02 (2018.01); A61P 35/00 (2018.01); A61P 37/06 (2018.01); C07D 519/00 (2013.01);
Abstract

A compound of formula (I) as Bruton's tyrosine kinase inhibitor, a preparation method therefor, and an application thereof in the field of medicine. The Bruton's tyrosine kinase inhibitor may be used for preventing and/or treating a disease related to Bruton's tyrosine kinase mediation, such as an autoimmune disease, cancer, or an inflammatory disease. Through experimental research, the provided compound has high selectivity with respect to a Bruton's tyrosine kinase target, and can exhibit a uniquely advantageous medicinal effect in an in vivo animal experiment.


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