The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2026

Filed:

Mar. 24, 2020
Applicants:

Shanghai Synergy Pharmaceutical Sciences Co., Ltd., Shanghai, CN;

Zhejiang Huahai Pharmaceutical Co., Ltd., Zhejiang, CN;

Inventors:

Xin Xu, Shanghai, CN;

Jia Chen, Shanghai, CN;

Zhen Zhang, Shanghai, CN;

Liming Zhang, Shanghai, CN;

Qimei Wu, Shanghai, CN;

Qingyun Jiang, Shanghai, CN;

Fengying Guo, Shanghai, CN;

Yuyun Zhang, Shanghai, CN;

Hao Yu, Shanghai, CN;

Ying Wang, Shanghai, CN;

Kang Sun, Shanghai, CN;

Chengxu Zang, Shanghai, CN;

Chenggang Qin, Shanghai, CN;

Xiaobo Zhou, Shanghai, CN;

Xiaojuan Zhang, Shanghai, CN;

Yijin Wang, Shanghai, CN;

Xiaoer Xia, Shanghai, CN;

Yunfei Li, Shanghai, CN;

Jian Ge, Shanghai, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 491/107 (2006.01); A61P 35/00 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 471/10 (2006.01); C07D 487/04 (2006.01); C07D 495/10 (2006.01);
U.S. Cl.
CPC ...
C07D 491/107 (2013.01); A61P 35/00 (2018.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 471/10 (2013.01); C07D 487/04 (2013.01); C07D 495/10 (2013.01);
Abstract

The present invention relates to a preparation method for an amide compound and an application thereof in the field of medicine. Specifically, provided by the present invention is an amide small molecule compound which is an inhibitor of Zeste gene enhancer homolog 2 (EZH2) and which may be used to prevent and/or treat EZH2-mediated related diseases, comprising tumors, myeloproliferative diseases or autoimmune diseases.


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