The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2026
Filed:
Nov. 20, 2020
Applicant:
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Inventors:
Adam Castoreno, Framingham, MA (US);
Elane Fishilevich, Rochester, MA (US);
Jason A. Gilbert, Hingham, MA (US);
Charalambos Kaittanis, Cambridge, MA (US);
James D. Mcininch, Burlington, MA (US);
Stuart Milstein, Arlington, MA (US);
Mark K. Schlegel, Lexington, MA (US);
Assignee:
ALNYLAM PHARMACEUTICALS, INC., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61P 25/28 (2018.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3515 (2013.01);
Abstract
The disclosure relates to double-stranded ribonucleic acid (dsRNA) agents and compositions targeting the ATXN3 gene, as well as methods of inhibiting expression of an APP gene and methods of treating subjects having an ATXN3-associated disease or disorder, such as SCA3, using such dsRNA agents and compositions.