The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2026
Filed:
Mar. 02, 2020
Peking University Third Hospital, Beijing, CN;
Institute of Chemistry, Chinese Academy of Sciences, Beijing, CN;
Jie Qiao, Beijing, CN;
Jie Yan, Beijing, CN;
Liying Yan, Beijing, CN;
Rong Li, Beijing, CN;
Jianjun Wang, Beijing, CN;
Shenglin Jin, Beijing, CN;
Jianyong Lv, Beijing, CN;
PEKING UNIVERSITY THIRD HOSPITAL, Beijing, CN;
INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES, Beijing, CN;
Abstract
A thawing solution has 0.1-50 g of a biomimetic material for controlling ice, 0-1.0 mol Lof a water-soluble sugar, and balance of a buffer solution. The biomimetic material for controlling ice is a material for controlling ice having an ice-philic group and a hydrophilic group. The hydrophilic group is a functional group that can form a non-covalent interaction with water molecules, and the ice-philic group is a functional group that can form a non-covalent interaction with ice. Using the thawing solution and the thawing reagent prepared from the biomimetic material for controlling ice, which material has ice-philic and hydrophilic properties, the growth and recrystallization of ice crystals can be effectively controlled, and damage to cells or tissue caused by uncontrolled growth of the ice crystals during recovery can be significantly ameliorated.