The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 20, 2026
Filed:
Dec. 18, 2020
Applicant:
University of Maryland, Baltimore, Baltimore, MD (US);
Inventors:
Vincent C. O. Njar, Glen Burnie, MD (US);
Senthilmurugan Ramalingam, Ellicott City, MD (US);
Lalji K. Gediya, Rockville, MD (US);
Hannah W. Mbatia, Cary, NC (US);
Vidya P. Ramamurthy, Ellicott City, MD (US);
Assignee:
UNIVERSITY OF MARYLAND, BALTIMORE, Baltimore, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 233/56 (2006.01); A61K 31/203 (2006.01); A61K 31/4164 (2006.01); A61P 17/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 233/56 (2013.01); A61P 17/00 (2018.01); A61K 31/203 (2013.01); A61K 31/4164 (2013.01); A61P 35/00 (2018.01);
Abstract
Novel retinamides with unique properties and biological activities, including inhibition of retinoic acid metabolism and modulation of Mnk1/2-eIF4E and androgen receptor (AR) signaling pathways, are synthesized and developed. The novel retinamides are capable of effecting treatment of a variety of dermatological conditions while limiting adverse side effects.