The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2026
Filed:
Dec. 07, 2023
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Jonathan Edward Farley, Boston, MA (US);
Mark K. Schlegel, Lexington, MA (US);
James D. Mcininch, Burlington, MA (US);
Jeffrey Zuber, Somerville, MA (US);
Adam Castoreno, Framingham, MA (US);
Stephen Abbott, Lexington, MA (US);
Joseph Barry, Arlington, MA (US);
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The disclosure relates to double stranded ribonucleic acid interference (dsRNAi) agents and compositions targeting a microtubule-associated protein tau (MAPT) gene, as well as methods of inhibiting expression of a MAPT gene and methods of treating subjects having a MAPT-associated disease or disorder, e.g., Alzheimer's disease, frontotemporal dementia, progressive supranuclear palsy, or other tauopathies, using such dsRNAi agents and compositions.