The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2025

Filed:

Jan. 13, 2023
Applicant:

Applied Materials, Inc., Santa Clara, CA (US);

Inventors:

Sumit Kumar Jha, Bangalore, IN;

Dan Xie, Pleasanton, CA (US);

Arina Nikitina, Samara, RU;

Debjit Ray, Santa Clara, CA (US);

Yun-Ching Chang, San Jose, CA (US);

Suraj Rengarajan, Bangalore, IN;

Assignee:

Applied Materials, Inc., Santa Clara, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G06T 7/00 (2017.01); G06T 5/00 (2024.01); G06T 5/70 (2024.01); G06T 7/11 (2017.01); G06V 10/82 (2022.01); G06V 20/70 (2022.01);
U.S. Cl.
CPC ...
G06T 7/0012 (2013.01); G06T 5/70 (2024.01); G06T 7/11 (2017.01); G06V 10/82 (2022.01); G06V 20/70 (2022.01); G06T 2207/30024 (2013.01);
Abstract

A system and method of performing deep cell body segmentation on a biological sample is provided. The method includes receiving a first and a second stained image. The first image is processed using a trained machine learned model that outputs locations of a plurality of cell nuclei in the first stained image. Seed points are then determined based on the locations of the plurality of cell nuclei. The second image is then processed using the seed points to determine a plurality of cell membranes using a watershed segmentation. The second image is then post-processed and an output image is produced. The output image is then analyzed and gene sequencing is performed.


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