The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2025

Filed:

Apr. 20, 2022
Applicant:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Inventors:

Murat Baday, Menlo Park, CA (US);

Naside Gozde Durmus, Palo Alto, CA (US);

Semih Calamak, Palo Alto, CA (US);

Utkan Demirci, Stanford, CA (US);

Ronald W. Davis, Palo Alto, CA (US);

Lars Steinmetz, San Francisco, CA (US);

Jaeyoung Yang, Palo Alto, CA (US);

Thiruppathiraja Chinnasamy, Mountain View, CA (US);

Alessandro Tocchio, San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B03C 1/28 (2006.01); B03C 1/32 (2006.01); G01N 15/14 (2006.01); G01N 33/487 (2006.01); G01N 33/543 (2006.01); G01N 33/569 (2006.01); G01N 33/574 (2006.01); G06T 7/00 (2017.01); G16H 30/40 (2018.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); B01L 3/502784 (2013.01); B03C 1/288 (2013.01); B03C 1/32 (2013.01); G01N 15/14 (2013.01); G01N 33/4875 (2013.01); G01N 33/54366 (2013.01); G01N 33/56966 (2013.01); G01N 33/574 (2013.01); G06T 7/0016 (2013.01); G16H 30/40 (2018.01); B01L 2200/0652 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/043 (2013.01); B03C 2201/18 (2013.01); B03C 2201/26 (2013.01); G01N 2015/1486 (2013.01); G06T 2207/30101 (2013.01); G06T 2207/30242 (2013.01); G06T 2211/428 (2013.01);
Abstract

A heterogeneous population of cells are separated and collected according to a method. The heterogeneous population of cells in a paramagnetic medium are placed in a fluidic channel in which the fluidic channel comprises two or more outlets. The heterogeneous population of cells in the fluidic channel are separated based on differences in magnetic susceptibility and density of the heterogeneous population of cells. Fluid comprising the separated cells is withdrawn from the two or more outlets using variable flow rates by fluidic pumps at respective ones of the two or more outlets simultaneously to fractionalize the fluid comprising the separated cells across the two or more outlets by manipulation of the variable flow rates relative to one another.


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