The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2025
Filed:
Mar. 13, 2024
Amgen Inc., Thousand Oaks, CA (US);
Rizwan Sharnez, Mead, CO (US);
William Trieu, Agoura Hills, CA (US);
Marc A. Caporini, Cambridge, MA (US);
Ron C. Kelly, Thousand Oaks, CA (US);
Neill Burt, Denver, CO (US);
Laura Nicholson, Boulder, CO (US);
Twinkle R. Christian, Thousand Oaks, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
Disclosed herein are methods of preparing a composition comprising crystalline biomolecules, for example, crystalline antibodies. In exemplary embodiments, the method comprises forming a fluidized bed of crystalline biomolecules using, for example, a counter-flow centrifuge to exchange buffer and/or to concentrate the crystalline biomolecules in a solution. Also provided are methods of detecting crystalline biomolecules and/or amorphous biomolecules in a sample.