The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 2025
Filed:
Jun. 24, 2022
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Osaka University, Osaka, JP;
Hitoshi Katada, Singapore, SG;
Kanako Tatsumi, Shizuoka, JP;
Yutaka Matsuda, Tokyo, JP;
Shun Shimizu, Shizuoka, JP;
Masaki Kamimura, Kanagawa, JP;
Yasunori Komori, Shizuoka, JP;
Yuji Hori, Shizuoka, JP;
Tomoyuki Igawa, Tokyo, JP;
Hiroki Kawauchi, Kanagawa, JP;
Hiroki Hayashi, Kanagawa, JP;
Hiroaki Susumu, Kanagawa, JP;
Shimon Sakaguchi, Osaka, JP;
CHUGAI SEIYAKU KABUSHIKI KAISHA, Tokyo, JP;
OSAKA UNIVERSITY, Osaka, JP;
Abstract
The present disclosure provides anti-CTLA-4 antibodies and methods of producing and using the antibodies. The present disclosure also provides nucleic acids encoding the anti-CTLA-4 antibodies and host cells containing the nucleic acids. Furthermore, the present disclosure provides polypeptides containing a variant Fc region containing amino acid alterations in a parent Pc region and methods of producing and using the polypeptides.