The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2025

Filed:

May. 31, 2021
Applicant:

Shaoxing Tongchuang Biotechnology Co., Ltd., Zhejiang, CN;

Inventors:

Mingfei Yao, Zhejiang, CN;

Shengyi Han, Zhejiang, CN;

Xin Jin, Zhejiang, CN;

Weixin Huang, Zhejiang, CN;

Jiaojiao Xie, Zhejiang, CN;

Yanmeng Lu, Zhejiang, CN;

Bona Wang, Zhejiang, CN;

Ling Gao, Zhejiang, CN;

Chihui Yu, Zhejiang, CN;

Lanjuan Li, Zhejiang, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A23L 33/135 (2016.01); A23L 29/212 (2016.01); A23L 29/262 (2016.01); A23L 29/275 (2016.01); A23P 10/30 (2016.01); A61K 9/48 (2006.01); A61K 9/50 (2006.01); A61K 35/00 (2006.01); A61K 35/747 (2015.01);
U.S. Cl.
CPC ...
A23L 33/135 (2016.08); A23L 29/212 (2016.08); A23L 29/262 (2016.08); A23L 29/275 (2016.08); A23P 10/30 (2016.08); A61K 9/4808 (2013.01); A61K 9/4866 (2013.01); A61K 9/5036 (2013.01); A61K 9/5089 (2013.01); A61K 35/747 (2013.01); A23V 2400/181 (2023.08); A61K 2035/115 (2013.01);
Abstract

The invention provides a Probiotic microcapsule and a preparation method thereof, relating to the technical field of Probiotic products. The method includes the following steps: (a) preparing a capsule core containing Probiotics: mixing the capsule core materials including Probiotic powder, microcrystalline cellulose and starch, then adding a hydroxypropyl methylcellulose solution thereinto, while mixing evenly, making the obtained mixture materials into spherical particulate capsule cores by the extrusion spherization method; (b) coating by atomization: coating the microcapsule cores with a coating material solution in a single layer or multiple layers by atomization, getting core-shell microcapsules. The Probiotic microcapsules prepared by the present invention have a large encapsulation, uniform microcapsule particles, controllable particle size, storage-resistance, targetability to intestinal tracts, resistance to gastric acids and high temperature stability.


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