The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 30, 2025
Filed:
Mar. 11, 2020
Applicants:
LA Jolla Institute for Immunology, La Jolla, CA (US);
The Regents of the University of California, Oakland, CA (US);
Inventors:
Stephen P. Schoenberger, San Diego, CA (US);
Bjoern Peters, San Diego, CA (US);
Alessandro Sette, San Diego, CA (US);
Jason Greenbaum, San Diego, CA (US);
Ezra Cohen, San Diego, CA (US);
Aaron Miller, San Diego, CA (US);
Assignee:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 40/42 (2025.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C12Q 1/6869 (2018.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
A61K 40/4201 (2025.01); A61P 35/00 (2018.01); C07K 14/4748 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6886 (2013.01);
Abstract
Systems and methods for identifying neoantigen peptide candidates are described. Such systems and methods can be used to generate engineered immune cells that target neoantigen peptides. In certain embodiments, the systems and methods do not require in silico epitope binding prediction algorithms. In certain embodiments, neoantigens are identified for a cancer or tumor with a low mutational burden.