The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2025
Filed:
Aug. 20, 2019
The Broad Institute, Inc., Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Amit Choudhary, Boston, MA (US);
Debasish Manna, Boston, MA (US);
Basudeb Maji, Cambridge, MA (US);
Soumyashree Ashok Gangopadhyay, Boston, MA (US);
The Broad Institute, Inc., Cambridge, MA (US);
The Brigham and Womens's Hospital, Inc., Boston, MA (US);
Abstract
The disclosure includes non-naturally occurring or engineered DNA- or RNA-guided nuclease systems, comprising CRISPR enzymes associated with at least one destabilization domain (DD) and photocaged stabilization ligands with at least one photocage molecule, along with compositions, systems and complexes involving such systems, nucleic acid molecules and vectors encoding the same, delivery systems involving the same, uses thereof.