The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2025
Filed:
Mar. 02, 2020
Peking University Third Hospital, Beijing, CN;
Institute of Chemistry, Chinese Academy of Sciences, Beijing, CN;
Jie Yan, Beijing, CN;
Jie Qiao, Beijing, CN;
Liying Yan, Beijing, CN;
Rong Li, Beijing, CN;
Jianjun Wang, Beijing, CN;
Shenglin Jin, Beijing, CN;
Jianyong Lv, Beijing, CN;
PEKING UNIVERSITY THIRD HOSPITAL, Beijing, CN;
INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES, Beijing, CN;
Abstract
A cryopreservation solution contains 0.01-50.0 g of bionic ice control materials, 5.0-30 mL of polyols, 1-30 g of water-soluble sugar, and 0-30 mL of serum, and a buffer in every 100 mL of the cryopreservation solution. It does not contain DMSO. When being used for the cryopreservation of mouse oocytes and embryos, the solution may achieve the same or an even higher cell and tissue survival rate and functional expression stability as or than a commercial cryopreservation solution (containing 15% DMSO), and has high preservation efficiency. The cryopreservation solution without DMSO or serum reduces parasitic biological contaminants in the commercial cryopreservation solution containing serum currently used in clinical practice.