The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2025

Filed:

Mar. 10, 2021
Applicant:

Dovetail Genomics, Llc, Scotts Valley, CA (US);

Inventors:

Richard E. Green, Jr., Santa Cruz, CA (US);

Daniel S. Rokhsar, Kensington, CA (US);

Paul Hartley, San Jose, CA (US);

Marco Blanchette, Santa Cruz, CA (US);

Assignee:

DOVETAIL GENOMICS, LLC, Scotts Valley, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6806 (2018.01); C12Q 1/68 (2018.01); C12Q 1/6869 (2018.01); C40B 40/06 (2006.01); C40B 40/08 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6869 (2013.01); C40B 40/06 (2013.01); C40B 40/08 (2013.01); G01N 33/5308 (2013.01);
Abstract

Disclosed herein are methods, compositions and systems that facilitate accurate phasing of sequence data such as genomic sequence data through the segmentation and rearrangement of nucleic acid molecules in such a way as to preserve individual molecules' phase or physical linkage information. This is variously accomplished by binding molecules independent of their phosphodiester backbones, cleaving the molecules, ligating, and sequencing the molecules through long-read sequencing technology to recover segment sequence information spanning at least more than one segment.


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