The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2025

Filed:

Jul. 23, 2019
Applicant:

The Governors of the University of Alberta, Edmonton, CA;

Inventors:

Ratmir Derda, Edmonton, CA;

Raja Mukherjee, Edmonton, CA;

Vivian Triana, Edmonton, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/10 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1037 (2013.01); C40B 40/10 (2013.01);
Abstract

The invention relates to a bicyclic peptide complex comprising a peptide construct, said construct comprising (i) a polypeptide with free terminus (N or C); (ii) optionally, a nucleic acid encoding the polypeptide; (iii) a twofold-symmetric linker (TSL) compound attached to said polypeptide where the linker is attached to the terminus of polypeptide via a covalent bond and to at least two discrete side chains of the peptide. The invention also relates to libraries, and to methods for making complexes and to methods of screening using the same.


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