The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2025
Filed:
Aug. 10, 2018
City of Hope, Duarte, CA (US);
California Institute of Technology, Pasadena, CA (US);
The General Hospital Corporation, Boston, MA (US);
Saumya Das, Boston, MA (US);
Ane Miren Salvador Garicano, Boston, MA (US);
Si-Ping Han, Duarte, CA (US);
Lisa Scherer, Duarte, CA (US);
Julia Derogatis, Duarte, CA (US);
Robin Hu, Duarte, CA (US);
Sahil Sagar, Duarte, CA (US);
William A. Goddard, Iii, Pasadena, CA (US);
John Rossi, Duarte, CA (US);
City of Hope, Duarte, CA (US);
California Institute of Technology, Pasadena, CA (US);
The General Hospital Corporation, Boston, MA (US);
Abstract
Disclosed herein are conditional siRNAs activatable by pro-hypertrophic RNA sequences and use thereof for treating conditions such as cardiac hypertrophy. The conditional siRNAs target calcineurin or HDAC2.