The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2025
Filed:
Mar. 10, 2020
Applicant:
Academia Sinica, Taipei, TW;
Inventors:
Chi-Huey Wong, Rancho Santa Fe, CA (US);
Hong-Jay Lo, New Taipei, TW;
Assignee:
Academia Sinica, Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/18 (2006.01); C07H 1/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07H 15/18 (2013.01); C07H 1/00 (2013.01); C07K 16/283 (2013.01); C07K 16/2887 (2013.01); C07K 2317/24 (2013.01); C07K 2317/41 (2013.01); C07K 2317/92 (2013.01);
Abstract
Disclosed are a method of preparing a saccharide that contains a 3-fluoro-sialic acid and a method of bonding it to a homogeneous antibody. Also within the scope of this invention are compounds each containing a 3-fluoro-sialic acid, monoclonal antibodies bonded to α2,6-linked 3-fluoro-sialo-side terminated N-glycans, and treatment of cancer with such monoclonal antibodies.