The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2025
Filed:
Jun. 22, 2018
Applicant:
Entos Pharmaceuticals Inc., Edmonton, CA;
Inventors:
Roy Duncan, Mineville, CA;
Chungen Pan, Guangzhou, CN;
Assignee:
ENTOS PHARMACEUTICALS INC., Edmonton, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); A61K 35/765 (2015.01); A61K 35/766 (2015.01); A61P 35/04 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 35/765 (2013.01); A61K 35/766 (2013.01); A61P 35/04 (2018.01); C12N 7/00 (2013.01); C07K 2319/03 (2013.01); C12N 2720/12022 (2013.01); C12N 2720/12033 (2013.01); C12N 2760/20221 (2013.01); C12N 2760/20232 (2013.01);
Abstract
Disclosed are recombinant oncolytic viruses that express one or more reovirus fusion-associated small transmembrane FAST) proteins and uses thereof. The oncolytic activity of the recombinant oncolytic viruses expressing FAST proteins can be used to treat primary and metastatic cancers, especially from breast and colon cancers.