The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

Aug. 13, 2020
Applicant:

Amyris, Inc., Emeryville, CA (US);

Inventors:

Jessica Walter, Emeryville, CA (US);

Dominic Pinel, Emeryville, CA (US);

Assignee:

Amyris, Inc., Emeryville, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/04 (2006.01);
U.S. Cl.
CPC ...
C12P 19/04 (2013.01); C12Y 101/01271 (2013.01); C12Y 204/01069 (2013.01); C12Y 204/01152 (2013.01); C12Y 204/99004 (2013.01); C12Y 205/01057 (2013.01); C12Y 207/07023 (2013.01); C12Y 207/07043 (2013.01); C12Y 306/03 (2013.01); C12Y 402/01047 (2013.01); C12Y 501/03014 (2013.01);
Abstract

Provided herein are genetically modified yeast cells capable of producing one or more human milk oligosaccharides (HMOs) and methods of making such cells. The yeast cells are engineered to comprise a heterologous nucleic acid encoding a transporter protein and one or more heterologous nucleic acids that encode enzymes of a HMO biosynthetic pathway. Also provided are fermentation compositions including the disclosed genetically modified yeast cells, and related methods of producing and recovering HMOs generated by the yeast cells.


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