The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2025
Filed:
Mar. 25, 2019
Applicants:
Massachusetts Eye and Ear Infirmary, Boston, MA (US);
Editas Medicine, Inc., Cambridge, MA (US);
Inventors:
Eric A. Pierce, Boston, MA (US);
Carrie Marie Margulies, Newton, MA (US);
Nachiket D. Pendse, Quincy, MA (US);
Sebastian W. Gloskowski, Malden, MA (US);
Qin Liu, Boston, MA (US);
Morgan L. Maeder, Cambridge, MA (US);
Assignees:
Massachusetts Eye and Ear Infirmary, Boston, MA (US);
Editas Medicine, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); A61K 48/00 (2006.01); C12N 15/113 (2010.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); A61K 48/0016 (2013.01); C12N 15/113 (2013.01); C12N 15/86 (2013.01); C12N 2310/20 (2017.05); C12N 2320/33 (2013.01); C12N 2750/14143 (2013.01);
Abstract
Compositions for use in treating subjects with USH2A-associated retinal and/or cochlear degeneration that result from mutations in exon 13 of the USH2A gene by deletion of exon 13 from the USH2A gene or transcripts, and methods of use thereof, as well as genetically modified animals and cells.