The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2025
Filed:
Jul. 03, 2019
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Kun Zhang, La Jolla, CA (US);
Yan Wu, La Jolla, CA (US);
Amir Dailamy, La Jolla, CA (US);
Prashant Mali, La Jolla, CA (US);
Daniella McDonald, La Jolla, CA (US);
Udit Parekh, La Jolla, CA (US);
Michael Hu, La Jolla, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61K 31/522 (2006.01); A61K 45/06 (2006.01); C12N 5/071 (2010.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4702 (2013.01); A61K 31/522 (2013.01); A61K 45/06 (2013.01); C12N 5/0697 (2013.01); C12N 9/22 (2013.01); C12N 15/111 (2013.01); C12N 15/86 (2013.01); C12N 2310/20 (2017.05);
Abstract
This disclosure relates to methods, polynucleotides, vectors, viral particles, cells, and systems or the engineering of human tissues. One aspect of the disclosure relates to using lineage-specific miRNA binding molecules to bias tissue lineage. Another aspect of the disclosure relates to using lineage-specific transcription factor overexpression to bias tissue lineage.