The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2025

Filed:

Sep. 09, 2022
Applicant:

Evonik Operations Gmbh, Essen, DE;

Inventors:

Silke Jerrentrup, Bielefeld, DE;

Brigitte Bathe, Salzkotten, DE;

Kornelia Voß, Antwerp, BE;

Frank Jankowitsch, Sassenberg, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/21 (2006.01); C07K 14/34 (2006.01); C12N 9/12 (2006.01); C12N 15/77 (2006.01); C12P 13/08 (2006.01);
U.S. Cl.
CPC ...
C12P 13/08 (2013.01); C07K 14/34 (2013.01); C12N 9/1217 (2013.01); C12Y 207/02004 (2013.01);
Abstract

strains express modified gluconate repressor proteins GntR1 and GntR2. Thestrains have an increased ability to produce L-lysine compared with an ability of a wildtype strain. The gluconate repressor protein GntR1 includes an amino acid sequence of SEQ ID NO: 9, where the amino acid Arg in position 102 is replaced by the amino acid Glu. The gluconate repressor protein GntR2 includes SEQ ID NO: 10, and its activity is attenuated compared to the activity of the GntR2 repressor protein of the wild-type strain. A method is developed for the fermentative production of L-lysine using suchstrains.


Find Patent Forward Citations

Loading…