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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12241081 B1

PDFFull Text
Date of Patent:
Mar. 04, 2025

Filed:

Aug. 03, 2018

B cell receptor modification in b cells

Applicant:

The Scripps Research Institute, La Jolla, CA (US);

Inventors:

James Even Voss, San Diego, CA (US);

Raiees Andrabi, San Diego, CA (US);

Dennis R. Burton, La Jolla, CA (US);

Deli Huang, La Jolla, CA (US);

Alicia Gonzalez-Martin, Madrid, ES;

Assignee:

The Scripps Research Institute, La Jolla, CA (US);

Attorneys:

Mark S. Cohen

PEARL COHEN ZEDEK LATZER BARATZ LLP

Primary Examiner:

Hong Sang

Assistant Examiner:

Carol Ann Chase

Int. Cl.
CPC ...
C12N 15/90 (2006.01); C07K 16/10 (2006.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C07K 16/1045 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/63 (2013.01); C07K 2317/76 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01);
Abstract

Methods and systems are described herein for generating engineered B cells with modified immunoglobulin genes. The modified immunoglobulin genes encode modified immunoglobulins that can have high affinity for antigens, including antigens that are variable such the types of antigens on various pathogens that can escape mammalian immune responses.

Find Patent Forward Citations

Voss, James. (2025). B cell receptor modification in b cells (U.S. Patent No. 12241081). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12241081

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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