The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 04, 2025
Filed:
Aug. 03, 2018
Applicant:
The Scripps Research Institute, La Jolla, CA (US);
Inventors:
James Even Voss, San Diego, CA (US);
Raiees Andrabi, San Diego, CA (US);
Dennis R. Burton, La Jolla, CA (US);
Deli Huang, La Jolla, CA (US);
Alicia Gonzalez-Martin, Madrid, ES;
Assignee:
The Scripps Research Institute, La Jolla, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/90 (2006.01); C07K 16/10 (2006.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C07K 16/1045 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/63 (2013.01); C07K 2317/76 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01);
Abstract
Methods and systems are described herein for generating engineered B cells with modified immunoglobulin genes. The modified immunoglobulin genes encode modified immunoglobulins that can have high affinity for antigens, including antigens that are variable such the types of antigens on various pathogens that can escape mammalian immune responses.