The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
May. 19, 2021
Applicant:
Janssen Biotech, Inc., Horsham, PA (US);
Inventors:
Vadim Dudkin, Chalfont, PA (US);
Shalom Goldberg, Merion Station, PA (US);
Michael J. McCauley, Abington, PA (US);
Kristen Wiley, Trappe, PA (US);
Rebecca Wissner, Philadelphia, PA (US);
Assignee:
Janssen Biotech, Inc., Horsham, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/32 (2006.01); A61K 47/68 (2017.01); C07K 16/28 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); A61K 47/68031 (2023.08); A61K 47/6849 (2017.08); C07K 16/2803 (2013.01); C12N 9/1044 (2013.01); C07K 2317/21 (2013.01); C07K 2317/32 (2013.01); C07K 2317/94 (2013.01); C12Y 203/02013 (2013.01);
Abstract
Engineered antibodies useful for site-specific conjugation by a transglutaminase are described. Also described are methods of site-specific conjugation of the antibodies, the site-specifically conjugated antibodies, and pharmaceutical compositions and uses related to the site-specifically conjugated antibodies.