The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 2025
Filed:
Jul. 21, 2021
Promab Biotechnologies, Inc., Richmond, CA (US);
Forevertek Biotechnology Co., Ltd, Changsha, CN;
Lijun Wu, Berkeley, CA (US);
Vita Golubovskaya, Pinole, CA (US);
Forevertek Biotechnology Co., Ltd, Changsha, CN;
ProMab Biotechnologies, Inc., Richmond, CA (US);
Abstract
The present invention is directed to a humanized monoclonal anti-human EpCAM antibody, such as a single-chain variable fragment (scFv), comprising Vhaving the amino acid of SEQ ID NO: 2 and Vhaving the amino acid of SEQ ID NO: 4. The present invention is also directed to a chimeric antigen receptor fusion protein comprising from N-terminus to C-terminus: (i) a single-chain variable fragment (scFv) of the present invention, (ii) a transmembrane domain, (iii) at least one co-stimulatory domains, and (iv) an activating domain.