The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 18, 2025

Filed:

Jul. 10, 2023
Applicant:

Sutro Biopharma, Inc., South San Francisco, CA (US);

Inventors:

Amandeep Gakhal, San Mateo, CA (US);

Abigail Yu, San Jose, CA (US);

Ryan Stafford, Foster City, CA (US);

Jeffrey Hanson, Oakland, CA (US);

Alice Yam, Belmont, CA (US);

Krishna Bajjuri, Union City, CA (US);

Andreas Maderna, Walnut Creek, CA (US);

Cristina Abrahams, Burlingame, CA (US);

Xiaofan Li, Belmont, CA (US);

Gang Yin, South San Francisco, CA (US);

Miao Wen, Union City, CA (US);

Kristin Bedard, Bellevue, WA (US);

Daniel Calarese, Millbrae, CA (US);

Helena Kiefel, South San Francisco, CA (US);

Assignee:

Sutro Biopharma, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 31/502 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6869 (2017.08); A61K 31/502 (2013.01); A61K 47/6803 (2017.08); A61K 47/6805 (2017.08); A61K 47/6809 (2017.08); A61K 47/6849 (2017.08); A61K 47/6889 (2017.08); A61P 35/00 (2018.01);
Abstract

The present disclosure relates to antibodies and antibody conjugates, for instance antibody drug conjugates, with binding specificity for receptor tyrosine kinase orphan receptor 1 (ROR1) and its isoforms and homologs, and compositions comprising the antibodies or antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibodies and antibody conjugates and compositions thereof as well as methods of using the antibodies and antibody conjugates and compositions thereof, such as in therapeutic and diagnostic methods.


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