The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 17, 2024

Filed:

Dec. 20, 2023
Applicant:

Nanjing Nutrabuilding Bio-tech Co., Ltd., Nanjing, CN;

Inventors:

Ronghua Yi, Nanjing, CN;

Qiru Fan, Nanjing, CN;

Mingru Wang, Nanjing, CN;

Ou Wang, Nanjing, CN;

Kylin Liao, Nanjing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4172 (2006.01); A61P 27/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4172 (2013.01); A61P 27/02 (2018.01);
Abstract

The present invention provides methods, compositions (e.g., eyedrop or spongarion composition), and uses for alleviating and preventing age-associated vitreous degeneration in a mammal, comprising administrating to the mammal in need thereof a therapeutically effective amount of L-ergothioneine, an analog or derivative thereof, or a pharmaceutically acceptable salt, acid, ester, polymer, analog or derivative thereof, as an active ingredient. In particular, L-ergothioneine is capable of scavenging chronic reactive oxygen species directly and radically to mitigate and prevent HA depolymerization and HA decreasing-viscosity in the mammal's vitreous body; and/or improving vitreous liquefaction in the mammal.


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