The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2024

Filed:

Jan. 14, 2021
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

J. Keith Joung, Winchester, MA (US);

Morgan Maeder, Brookline, MA (US);

James Angstman, Charlestown, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0071 (2013.01); C07K 2319/80 (2013.01); C07K 2319/81 (2013.01);
Abstract

Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array or zinc finger, and a catalytic domain comprising a sequence that catalyzes hydroxylation of methylated cytosines in DNA, and methods of use thereof.


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