The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2024
Filed:
Aug. 25, 2017
National Research Institute of Brewing, Higashihiroshima, JP;
Fasmac Co., Ltd., Atsugi, JP;
Kazuhiro Iwashita, Higashihiroshima, JP;
Ken Oda, Higashihiroshima, JP;
Kohei Shimamoto, Higashihiroshima, JP;
Yusaku Wada, Atsugi, JP;
NATIONAL RESEARCH INSTITUTE OF BREWING, Higashihiroshima, JP;
FASMAC CO., LTD., Atsugi, JP;
Abstract
The present invention relates to a method of editing a filamentous fungal genome by direct introduction of a genome editing protein molecule or complex. The method includes three modes. In the first mode, a genome editing protein molecule or complex for a target gene is directly introduced into a cell of anfungus, to edit a gene in thefungal genome. In the second mode, a genome editing protein molecule or complex for a target region in a filamentous fungal genome, and a desired DNA fragment, are directly introduced into a filamentous fungal cell, to knock-in the DNA fragment to a desired target site in the filamentous fungal genome. In the third mode, genome editing protein molecules or complexes for plural target genes are directly introduced into a filamentous fungal cell, to carry out simultaneous editing of the plural genes in the filamentous fungal genome.